Comparison of Drug Dosing Recommendations Based on Measured GFR and Kidney Function Estimating Equations
نویسندگان
چکیده
منابع مشابه
Assessment of kidney function for drug dosing.
The effort to improve the identification and management of patients with chronic kidney disease (CKD) is based on implementing more precise means of assessing kidney function and kidney damage in the clinical setting. Over the past decade, the clinical chemistry community has adopted routine reporting of estimated GFR (eGFR) calculated from the Modification of Diet in Renal Disease (MDRD) Study...
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15 صفحه اولAccuracy of different equations in estimating GFR in pediatric kidney transplant recipients.
BACKGROUND AND OBJECTIVE The knowledge of renal function is crucial for the management of pediatric kidney transplant recipients. In this population, the most commonly used plasma creatinine (PCr)-based or cystatin C (CystC)-based GFR-predicting formulas may underperform (e.g., corticosteroids and trimethoprim may affect PCr concentration, whereas prednisone and calcineurin inhibitors may affec...
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15 صفحه اولEstimated GFR vs creatinine clearance for drug dosing.
Stevens et al suggest that the Modification of Diet in Renal Disease (MDRD) Study equation for estimated glomerular filtration rate (GFR) is an acceptable substitute for estimated or measured creatinine clearance (CCr) as an index for adjusting drug doses in patients with chronic kidney disease and acute kidney injury. However, others have raised concerns that injudicious use of estimated GFR a...
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ژورنال
عنوان ژورنال: American Journal of Kidney Diseases
سال: 2009
ISSN: 0272-6386
DOI: 10.1053/j.ajkd.2009.03.008